AFCON 2025: South Africa vs Cameroon preview, prediction, team news and head-to-head

Both nations are former champions of the continent and with a place in the quarter-finals on the line, this knockout encounter promises to be an interesting one between two of Africa's giants.

South Africa enter this fixture following a thrilling 3-2 victory against Zimbabwe in their final group match, a result that secured their progression to the knockout phase. 

Hugo Broos will be facing a familiar opponent in Cameroon, the nation he famously led to AFCON glory in 2017. 

Bafana Bafana have been notoriously difficult to beat in recent months, losing only one of their last nineteen matches across all competitions.

However, they must improve their defensive concentration after conceding three goals in their last two outings.

Cameroon, meanwhile, secured their spot in the round of 16 with a hard-fought 2-1 win over Mozambique. The Indomitable Lions finished second in their group and remain unbeaten in the tournament thus far. 

Despite institutional turmoil surrounding the coaching staff and federation back home, the players have remained professional on the pitch. 

They will look to leverage their physicality and tournament experience to overcome a South African side that prides themself on slick passing and possession.

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Bafana Bafana have a surprisingly strong record against the Indomitable Lions in their five previous meetings. 

Cameroon have never defeated South Africa in a competitive fixture, with the Bafana Bafana winning two of their last five meetings.

The last two encounters between these sides both ended in draws during the 2016 AFCON qualification campaign, finishing 2-2 and 0-0 respectively. 

South Africa do not have any injury concern heading into this clash, with Broos having his full team available for the game.

Lyle Foster is expected to lead the line again as he searches for more goals in the knockout rounds.

Cameroon have only one injury concern, with Nouhou sustaining an injury during the group stage. Despite this, other players are available to face South Africa.

South Africa (4-2-3-1): Williams; Mudau, Ngezana, Mbokazi, Modiba; Mokoena, Sithole; Appollis, Mbule, Moremi; Foster

Cameroon (4-2-3-1): Epassy; Nyamsi, Boyomo, Tolo, Baleba; Kemen, Nagida; Namaso, Mbeumo, Kofane; Magri

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South Africa will look to dominate the ball and use their creative midfielders to unlock the Cameroon defence. 

However, Cameroon are master of grinding out results in knockout football and possess a significant physical advantage in set-piece situations. 

Given that five of their nine previous meetings have ended in draws, another stalemate after ninety minutes is a distinct possibility.