Nigeria secured a spot in the semi-final after a 2-0 win over Algeria in the Africa Cup of Nations quarter-final.
The Nigerian international played a key role in the defence and helped the Super Eagles keep a clean sheet.
The Birmingham City player appeared to be in pain late in the match at Stade de Marrakech, sparking fears he could miss the crucial semi-final clash with host nation Morocco.
Osayi speaks on injury scare
Osayi-Samuel quickly clarified that the issue was not a serious injury and he is ready for the clash against Morocco.
Speaking after the game, the versatile defender explained that he was suffering from cramps, not a knock.
"No, I had cramps. My toes were cold and I couldn’t move them, but I’ll be fine, absolutely fine," he stated, reassuring fans of his availability for the next round.
This news will come as a relief to Nigerian supporters, as Osayi-Samuel has become a key figure for the team during the tournament.
The former Fenerbahce star has delivered impressive performances, providing defensive stability and an attacking threat from the right flank.
With fellow defenders Ola Aina and Benjamin Frederick sidelined by injury, Osayi-Samuel's role has become even more critical to the Super Eagles' structure.
His fitness will be vital as Nigeria prepares to face a formidable Moroccan side in their quest for a fourth continental championship.