Bukayo Saka and Leandro Trossard suffered injuries during Arsenal's friendly match against Tottenham.
Arsenal came into the game on the back of a back-to-back win against AC Milan and Newcastle in their previous game.
However, the Gunners lost 1-0 to last season's Europa League winners in their preseason game held in Hong Kong.
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Saka and Trossard's injury
Saka was injured in a collision with Spurs forward Mathys Tel. The Arsenal and England winger went down clutching his thigh.
He received medical attention during halftime but was substituted in the 77th minute by 15-year-old Max Doman, as reported by Sportal.
In the 85th minute, forward Trossard was also substituted due to injury, having come on as a substitute in the 68th minute for Gabriel Martinelli.
Following the loss, the Gunners are still in the market for a winger and a midfielder to improve their squad, with Eberechi Eze being linked with a move to the Emirates.
Spurs will play a friendly against Newcastle on August 3rd, while Arsenal face Villarreal in another preseason test three days later.
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